Actin, Smooth Muscle (Leiomyosarcoma Marker); Clone 1A4 (Concentrate)
Actin, Smooth Muscle (Leiomyosarcoma Marker); Clone 1A4 (Concentrate)

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Code : RA0001-C.5
Species: Mouse Immunogen: N-terminal decapeptide of alpha smooth muscle isoform of actin and conjugated to KLH. Clone: 1A4 Isotype: IgG2a, kappa Species Reactivity: Human, Baboon, Monkey, Cow, Pig, Sheep, Goat, Cat, Dog, Rabbit, Mouse, Rat, Guinea Pig and Chicken. Others not known. Positive Control: Blood vessels in all tissues, smooth muscle or leiomyosarcoma. Specificity: This MAb is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin. Status: RUO
0.5 ml
Clone 1A4
Isotype IgG2a, kappa
Application IHC
Host Mouse
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