- Electron Microscopy
p504S/Alpha-Methylacyl-CoA Racemase (AMACR) (13H4)
P504S has been recently described as a prostate cancer-specific gene that encodes a protein involved in the ?-oxidation of branched chain fatty acids. Expression of p504S protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. P504S can be used as a positive marker for PIN.